Welcome to The Karpeles Manuscript Library Museum which opened to the public in 2006. Originally built in 1911 and designed by architect Solon Spencer Beman, this notable structure was the former First Church of Christ, Scientist. The architecture is a striking example of Neo-Classical and Greek Revival design, featuring a six-columned portico, fluted Ionic columns, a classic porch, and a pediment. Its unique asymmetric design perfectly complements the corner lot, and the building was recently featured in the film Nightmare Alley.
The interior and exterior spaces of this Buffalo icon provide an exceptional backdrop for any future use. The interior offers a cavernous foyer leading into a large, pillared hall with terrazzo flooring and a coffered ceiling. A lit canopy arches across the former sanctuary, highlighting the building’s distinctive classical elements. The exterior is defined by rough-textured masonry contrasted with vibrant red roof tiles and 25-foot picture windows.
Being sold as-is condition. Offers Due by 2:00pm Monday 2/9/26. Email proof of funds and Contract, required. LOI will not be accepted.
The interior and exterior spaces of this Buffalo icon provide an exceptional backdrop for any future use. The interior offers a cavernous foyer leading into a large, pillared hall with terrazzo flooring and a coffered ceiling. A lit canopy arches across the former sanctuary, highlighting the building’s distinctive classical elements. The exterior is defined by rough-textured masonry contrasted with vibrant red roof tiles and 25-foot picture windows.
Being sold as-is condition. Offers Due by 2:00pm Monday 2/9/26. Email proof of funds and Contract, required. LOI will not be accepted.
Property Details
Price:
$350,000
MLS #:
B1659657
Status:
Pending
Beds:
0
Baths:
0
Type:
Commercial
Subdivision:
West Side
Neighborhood:
buffalocity140200
Listed Date:
Jan 27, 2026
Finished Sq Ft:
31,576
Total Sq Ft:
31,576
Year Built:
1911
See this Listing
Schools
School District:
Buffalo
Interior
Heating
Gas, Other, See Remarks, Hot Water
Levels
Two
Exterior
Construction Materials
Other
Lot Features
Rectangular, Rectangular Lot
Roof
Asphalt, Flat, Membrane, Rubber
Stories
2
Financial
Taxes
$40,936
Map
Community
- Address220 North Street Buffalo NY
- CityBuffalo
- CountyErie
- Zip Code14201
Subdivisions in Buffalo
- 200 Delaware Condo
- 770 West Ferry Condo
- 800 West Ferry Condo
- Admirals Walk Condo
- Allentown
- Appollos Stevens
- Bailey Estate
- Bailey Estates
- Bailey-Lovejoy
- Berkshire Terrace
- Bird Farm
- Black Rock
- Bronson Park
- Bryant Parish Condo
- Buffal0 Crk Reservation
- Buffalo
- Buffalo Creek Reservation
- Buffalo Crk
- Buffalo Crk Indian Reserv
- Buffalo Crk Reservation
- Buffalo Stove Works Prop
- Carriage Lane Condo Bldg
- Central Park
- City Centre Condo
- City Of Buffalo
- City/Buffalo
- Cold Springs
- Colvin Estates
- Colvin Park
- Colvin Park New 04
- Delaware District
- Delaware Tower
- Delaware Tower Condo
- Delaware Tower Condos
- Downtown
- Drexel Add
- Drexel Sub
- East Side
- Ebenezer Lands
- Elmwood
- Elmwood Strip
- Estate/James H Metcalfe
- Executive Condo
- Ferry
- Ferry Lt
- Fillmore Leroy
- First Ward
- Fruit Belt
- Gore
- Gore Tr
- Hamlin Park
- Highland Park
- Historic Warehouse Condo
- Holland Company’s Surv
- Holland Land
- Holland Land Co
- Holland Land Companies Su
- Holland Land Company
- Holland Land Company ‘s S
- Holland Land Company Surv
- Holland Land Company’s Su
- Holland Land Companys
- Holland Land Companys Sur
- Holland Land Cos Curv
- HOLLAND LAND COS SURV
- Holland Land’s Company Su
- Holland Lands Company’s S
- Homes Tr
- Hospital Hill
- Humboldt Park
- James Sperry’s Surv
- Jones
- Jones Tr
- Kaisertown
- Kensington
- Kensington Park
- Land Company’s Surv
- Lands/The Richmond Avenue
- Lang Field Sub Map #2
- Lee & Mcphersons Sub
- Lower West Side
- Manns Plan
- Marina Park Condo B Bldg
- Masten Park
- New York State Reservatio
- Niagara
- North Buffalo
- Parish
- Parish Tr
- Parkside
- Pasquale Condo
- Polonia
- Rivermist Dev Ph 1
- Riverside
- Schiller Park
- South Buffalo
- South Vlg/Black Rock
- St Marys Square Condo
- Steven’s Surv
- Stevens Surv
- University District
- University Heights
- University Park Sub
- Waterfront Village Pt I
- Waterfront Village Pt Ii
- West Side
- Willert Park
- Willert Park Village Ph 1
Market Summary
Current real estate data for Commercial in Buffalo as of Jul 17, 2026
116
Commercial Listed
156
Avg DOM
84
Avg $ / SqFt
$507,584
Avg List Price
Property Summary
- 220 North Street Buffalo NY is a Commercial for sale in Buffalo, NY, 14201. It is listed for $350,000
Similar Listings Nearby
Courtesy of Gurney Becker & Bourne. Disclaimer: All data relating to real estate for sale on this page comes from the Broker Reciprocity (BR) of the New York State Alliance of MLSs. Detailed information about real estate listings held by brokerage firms other than Michael Paduano include the name of the listing broker. Neither the listing company nor Michael Paduano shall be responsible for any typographical errors, misinformation, misprints and shall be held totally harmless. The Broker providing this data believes it to be correct, but advises interested parties to confirm any item before relying on it in a purchase decision. Copyright 2026. New York State Alliance of MLSs. All rights reserved. 220 North Street
Buffalo, NY

