Well-maintained, single-story commercial building at 105 N Main Street in North Syracuse, NY. This 2,244 square foot medical office has been in continuous professional use for over 60 years and currently houses an established optometry practice operating at this location for 29 years. The building sits on a 0.23-acre lot with 15 dedicated parking spaces and offers high visibility on North Main Street.
The property received a new roof in 2024, significantly reducing near-term capital expenditure risk for the buyer. The interior features a professionally designed layout with reception and optical retail areas, multiple fully equipped exam rooms, private offices, and a laboratory space. The floor plan is well-suited for optometry, ophthalmology, dental, dermatology, chiropractic, physical therapy, counseling, or general professional office use.
Key property details: 2,244 SF on a single level. Built in 1950, well-maintained with a modern interior buildout. New roof installed in 2024. 15 on-site parking spaces (approximately 7 per 1,000 SF). Zoned for medical and professional office use. Single-tenant, owner-occupied.
This property is located in the heart of North Syracuse, within the rapidly growing Central New York economic corridor. The area is positioned to benefit significantly from the Micron Technology semiconductor fabrication facility currently under construction in nearby Clay, NY, which is expected to bring substantial job growth and commercial demand to the surrounding communities.
The building is available on its own at $400,000 or as part of a package with the established optometry practice (offered separately at $550,000). Seller financing may be available for qualified buyers.
The property received a new roof in 2024, significantly reducing near-term capital expenditure risk for the buyer. The interior features a professionally designed layout with reception and optical retail areas, multiple fully equipped exam rooms, private offices, and a laboratory space. The floor plan is well-suited for optometry, ophthalmology, dental, dermatology, chiropractic, physical therapy, counseling, or general professional office use.
Key property details: 2,244 SF on a single level. Built in 1950, well-maintained with a modern interior buildout. New roof installed in 2024. 15 on-site parking spaces (approximately 7 per 1,000 SF). Zoned for medical and professional office use. Single-tenant, owner-occupied.
This property is located in the heart of North Syracuse, within the rapidly growing Central New York economic corridor. The area is positioned to benefit significantly from the Micron Technology semiconductor fabrication facility currently under construction in nearby Clay, NY, which is expected to bring substantial job growth and commercial demand to the surrounding communities.
The building is available on its own at $400,000 or as part of a package with the established optometry practice (offered separately at $550,000). Seller financing may be available for qualified buyers.
Property Details
Price:
$400,000
MLS #:
S1683136
Status:
Active
Beds:
0
Baths:
0
Type:
Commercial
Subtype:
Office
Neighborhood:
northsyracusevillageclay312401
Listed Date:
May 19, 2026
Finished Sq Ft:
2,244
Total Sq Ft:
2,244
Lot Size:
10,094 sqft / 0.23 acres (approx)
Year Built:
1950
See this Listing
Schools
School District:
North Syracuse
Interior
Cooling
Central Air
Heating
Electric, Gas, Forced Air
Levels
One
Exterior
Building Features
Office, Phone System
Construction Materials
Wood Siding
Lot Features
Rectangular, Rectangular Lot
Parking Spots
15
Parking Total
15
Roof
Asphalt
Security Features
Intercom
Stories
1
Financial
Taxes
$10,374
Map
Community
- Address105 North Main Street Clay NY
- CityClay
- CountyOnondaga
- Zip Code13212
Subdivisions in Clay
- Amity Acres Tr
- Cherry Estates
- Cherry Heights Sec A
- Cherry Heights Tr Sec D-1
- Clairmont Park Sec C
- Clay
- Clay Marketplace
- Clearview Hts Tract
- Cross Crk Sub
- Fairway East
- Fairway East Sec #4
- Fairway East Sec 2
- Harke Farms Sec 1
- Heritage Tr Sec 2
- Horseshoe Island
- Hoyt
- Hoyt Tr
- Kalview Park
- Lawton Valley
- Madison Village
- Maple Manor Anx
- Marlin Mdws
- Merrill Farms Sec 3
- North Syracuse
- Northfield Acres
- Northtown Park Sec A
- Northwood Manor
- Pine Gate South
- Ranch Vly Homes
- Riverwalk
- Streamwood Sec B
- Summa Acres Sec 1
- The Farmstead
- Town/Clay
- WATERFRONT
- Waterhouse Landing
- Waterhouse Lndg Sec 1
- Westview Acres Sec A
- Wildflower
- Willow Stream
- Willowstream Wood Sec 3
- Wood-Glen Manor Tract
Market Summary
Current real estate data for Commercial in Clay as of May 25, 2026
15
Commercial Listed
631
Avg DOM
1,703
Avg $ / SqFt
$3,404,333
Avg List Price
Property Summary
- 105 North Main Street Clay NY is a Commercial for sale in Clay, NY, 13212. It is listed for $400,000
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Courtesy of Home With Us Realty Group, LLC. Disclaimer: All data relating to real estate for sale on this page comes from the Broker Reciprocity (BR) of the New York State Alliance of MLSs. Detailed information about real estate listings held by brokerage firms other than Michael Paduano include the name of the listing broker. Neither the listing company nor Michael Paduano shall be responsible for any typographical errors, misinformation, misprints and shall be held totally harmless. The Broker providing this data believes it to be correct, but advises interested parties to confirm any item before relying on it in a purchase decision. Copyright 2026. New York State Alliance of MLSs. All rights reserved. 105 North Main Street
Clay, NY

