Welcome to The Karpeles Manuscript Library Museum which opened to the public in 2006. Originally built in 1911 and designed by architect Solon Spencer Beman, this notable structure was the former First Church of Christ, Scientist. The architecture is a striking example of Neo-Classical and Greek Revival design, featuring a six-columned portico, fluted Ionic columns, a classic porch, and a pediment. Its unique asymmetric design perfectly complements the corner lot, and the building was recently featured in the film Nightmare Alley.
The interior and exterior spaces of this Buffalo icon provide an exceptional backdrop for any future use. The interior offers a cavernous foyer leading into a large, pillared hall with terrazzo flooring and a coffered ceiling. A lit canopy arches across the former sanctuary, highlighting the building’s distinctive classical elements. The exterior is defined by rough-textured masonry contrasted with vibrant red roof tiles and 25-foot picture windows.
Being sold as-is condition.
The interior and exterior spaces of this Buffalo icon provide an exceptional backdrop for any future use. The interior offers a cavernous foyer leading into a large, pillared hall with terrazzo flooring and a coffered ceiling. A lit canopy arches across the former sanctuary, highlighting the building’s distinctive classical elements. The exterior is defined by rough-textured masonry contrasted with vibrant red roof tiles and 25-foot picture windows.
Being sold as-is condition.
Property Details
Price:
$350,000
MLS #:
B1659657
Status:
Active
Beds:
0
Baths:
0
Type:
Commercial
Subdivision:
West Side
Neighborhood:
buffalocity140200
Listed Date:
Jan 27, 2026
Finished Sq Ft:
31,576
Total Sq Ft:
31,576
Year Built:
1911
See this Listing
Schools
School District:
Buffalo
Interior
Heating
Gas, Other, See Remarks, Hot Water
Exterior
Construction Materials
Other
Roof
Asphalt, Flat, Membrane, Rubber
Financial
Taxes
$40,936
Map
Community
- Address220 North Street Buffalo NY
- CityBuffalo
- CountyErie
- Zip Code14201
Subdivisions in Buffalo
- 200 Delaware Condo
- 200 Delaware Residential
- 770 West Ferry Condo
- 800 West Ferry Condo
- 900 Delaware Condo
- Admirals Walk Condo
- Allentown
- Apollos Stevens Surv
- Appollo Stevens Surv
- Appollos Stevens Surv
- Bailey Estate 01
- Bailey Estates
- Bailey-Lovejoy
- Barker Square Condo
- Berkshire Terrace
- Bethune Lofts
- Bird Farm
- Black Rock
- Boulevard Land Co
- Bryant Parish Condo
- Buffalo
- Buffalo Crk Erservation
- Buffalo Crk Indian Reserv
- Buffalo Crk Resermation
- Buffalo Crk Reservation
- Buffalo Crk Sub
- Central Park
- City Centre Condo
- City/Buffalo
- Cold Springs
- Colvin Estates
- Colvin Park 01
- Colvin Park Map #4
- Colvin Park Sub Map #1
- Colvin Park Sub Map #2
- Congress Street
- Copeland Place
- Delaware District
- Delaware Tower
- Delaware Tower Condo
- Delaware Tower Condos
- Downtown
- East Side
- Elmwood
- Elmwood Strip
- Estate/James H Metcalfe
- Executive Condo
- Ferry
- Ferry Lt
- Fillmore Leroy
- First Ward
- Fruit Belt
- Garner
- Georgian Village Condo
- Gore
- Gore Tr
- Hamlin Park
- Highland Park
- Historic Warehouse Condo
- Historic Warehouse LLC
- Holland
- Holland Land
- Holland Land Co
- Holland Land Companies Su
- Holland Land Company
- Holland Land Company Surv
- Holland Land Company’s
- Holland Land Company’s Su
- Holland Land Companys
- Holland Land Companys Sub
- Holland Land Companys Sur
- Holland Land Compnay’s Su
- HOLLAND LAND COS SURV
- Holland Lands Company’s S
- Homes Tr
- Hospital Hill
- Humboldt Park
- Jones
- Jones Tr
- Jones Tract
- Judge’s Row
- Kaisertown
- Kensington
- Kensington Heights
- Kensington Park
- Lang Field Sub Map #2
- Late South Vlg/Black Rock
- Late Vlg/Black Rock
- Lee & Mcphersons Sub
- Lower West Side
- M Davey’s Surv
- Manns Plan
- Masten
- Masten Park
- Mile Reserve
- N3384/0001
- New York State Reservatio
- Niagara
- North Buffalo
- Ogden Gore Tr
- Parish
- Parish Tr
- Parish Tract
- Park Gardens Sub 1
- Park Gardens Sub 5
- Park Land Associations
- Park Lane Condo
- Park Meadow
- Park View Estates
- Parkside
- Pasquale Condo
- Polonia
- River View Land Co
- Rivermist Dev Ph 1
- Riverside
- Schiller Park
- Section 89 70
- South Buffalo
- South Park Sub
- South Village Black Road
- South Village Black Rock
- South Village/Black Rock
- South Vlg/Black Rock
- St Marys Square Condo
- Stevens Surv
- Symphony Circle Condo
- Tivoli Gardens Condo
- University District
- University Heights
- University Park Sub
- Vernon Triangle
- Waterfront Village Pt II
- Waterloo-Hubbell Sub
- West End Condo Bldg
- West Side
- Willert Park
- Woodside Land Co
Market Summary
Current real estate data for Commercial in Buffalo as of Feb 05, 2026
102
Commercial Listed
154
Avg DOM
124
Avg $ / SqFt
$609,512
Avg List Price
Property Summary
- 220 North Street Buffalo NY is a Commercial for sale in Buffalo, NY, 14201. It is listed for $350,000
Similar Listings Nearby
Courtesy of Gurney Becker & Bourne. Disclaimer: All data relating to real estate for sale on this page comes from the Broker Reciprocity (BR) of the New York State Alliance of MLSs. Detailed information about real estate listings held by brokerage firms other than Michael Paduano include the name of the listing broker. Neither the listing company nor Michael Paduano shall be responsible for any typographical errors, misinformation, misprints and shall be held totally harmless. The Broker providing this data believes it to be correct, but advises interested parties to confirm any item before relying on it in a purchase decision. Copyright 2026. New York State Alliance of MLSs. All rights reserved. 220 North Street
Buffalo, NY

